維他命C是屬於體內重要的抗氧化劑,很多人當聽到維他命C直覺就會想到是可以抗老、去斑、美白讓皮膚緊實增加皮膚彈性等優點(可以抑制酪胺酸酶Tyrosinase 黑色素的形成,達到肌膚白皙)。其實維他命C擁有保護蛋白質、脂質免於受到自由基的破壞,一般接受高單位維他命C靜脈注射(IV)可以預防疾病、包含高血壓、癌症⁹、糖尿病、心血管疾病等⁷。過去有文獻研究顯示高單位維他命C可降低人體輸血感染的機會⁸,而維他命C屬於水溶性物質耐受性也高副作用也低¹¹,所以許多醫師診所都會很喜歡透過靜脈注射來使用。
靜脈注射維生素C一般在臨床試驗中耐受性良好。少數人因濃度問題,輸注過程中可能產生些微刺痛、頭痛、胃痙攣、頭暈、噁心感、口渴的感覺,但在數小時內恢復正常。維他命C會有利尿作用,會加速身體排出水分,務必注射後補充300~500CC水份。
參考資料:
1.Raymond YC, et al.: Effects of High Doses of Vitamin C on Cancer Patients in Singapore: Nine Cases. 2016
2.Seo MS, et al.: High-Dose Vitamin C Promotes Regression of Multiple Pulmonary Metastases Originating from Hepatocellular Carcinoma. 2015
3.Hoffer LJ, et al.: High-dose intravenous vitamin C combined with cytotoxic chemotherapy in patients with advanced cancer: a phase I-II clinical trial. 2015
4.Salerno JP. : High dose IV vitamin C for treatment of prostate adenocarcinoma. 2013
5.Takahashi H, et al.: High-dose intravenous vitamin C improves quality of life in cancer patients. 2012
6.Vollbracht C, Schneider B, Leendert V, et al.: Intravenous vitamin C administration improves quality of life in breast cancer patients during chemo-/radiotherapy and aftercare: results of a retrospective, multicentre, epidemiological cohort study in Germany. Vivo, 2011
7.Journal of the American college of Nutrition, Vol.22 no1 18-35(2003)
8.Journal of the International academy of medicine,1978 volume 5, number 1, pp. 54-58
9.CMAJ March 28 2006 174(7)
10.Levine M et al JAMA 1999;281:1415-1423
11.J am collnutr1995; 14:124-136
靜脈注射維生素C一般在臨床試驗中耐受性良好。少數人因濃度問題,輸注過程中可能產生些微刺痛、頭痛、胃痙攣、頭暈、噁心感、口渴的感覺,但在數小時內恢復正常。維他命C會有利尿作用,會加速身體排出水分,務必注射後補充300~500CC水份。
參考資料:
1.Raymond YC, et al.: Effects of High Doses of Vitamin C on Cancer Patients in Singapore: Nine Cases. 2016
2.Seo MS, et al.: High-Dose Vitamin C Promotes Regression of Multiple Pulmonary Metastases Originating from Hepatocellular Carcinoma. 2015
3.Hoffer LJ, et al.: High-dose intravenous vitamin C combined with cytotoxic chemotherapy in patients with advanced cancer: a phase I-II clinical trial. 2015
4.Salerno JP. : High dose IV vitamin C for treatment of prostate adenocarcinoma. 2013
5.Takahashi H, et al.: High-dose intravenous vitamin C improves quality of life in cancer patients. 2012
6.Vollbracht C, Schneider B, Leendert V, et al.: Intravenous vitamin C administration improves quality of life in breast cancer patients during chemo-/radiotherapy and aftercare: results of a retrospective, multicentre, epidemiological cohort study in Germany. Vivo, 2011
7.Journal of the American college of Nutrition, Vol.22 no1 18-35(2003)
8.Journal of the International academy of medicine,1978 volume 5, number 1, pp. 54-58
9.CMAJ March 28 2006 174(7)
10.Levine M et al JAMA 1999;281:1415-1423
11.J am collnutr1995; 14:124-136
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